The best time to ... apply acne treatmentsWhen: In the morning, right after you wake up
Why: According to Downie, the sebum (a.k.a. oil) level in your skin is at its lowest during the night, and at its highest in the morning. Thus, acne-fighting treatments are more effective when you apply them first thing in the morning when your skin is oiliest. However, Downie notes that while your skin's sebum level is higher during the day, skin cells turn over more frequently at night. If you suffer from moderate to severe acne, she advises applying treatments twice a day, morning and night, to take advantage of these daily changes that occur in your skin.
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