Anyone who's ever gotten a giant zit the day of a job interview, test or (ugh) her wedding understands that there's a link between stress and acne. And the connection is clear for dermatologists, as well: Stress increases levels of the hormone cortisol, which leads to breakouts. The best way to keep your cortisol levels in check is to relax. Go for a walk. Meditate. Go to bed early. Exercise. Hang out with friends. Hey, you can even use your skin as an excuse to plan a vacation. Figure out what works for you and do it daily.